Electrical recordings from rat cardiac muscle cells using field-effect transistors

Extracellular electrophysiological recordings were made from cardiac cells cultured for up to seven days over microfabricated arrays of field-effect t ransistors. The recorded signals dan be separated mainly into two types of cell transistor couplings: one that can be explained entirely by purely pas sive circuitry elements, and a second where voltage-gated ion channels cont ribute greatly to the measured extracellular signal. [S1063-651X(99)12008-7 ].