Reformatsky-type addition of esters of alpha-halogeno carboxylic acids to aldehydes and ketones in the presence of Fe(CO)(5)

Authors
Terent'ev, AB Vasil'eva, TT Kuz'mina, NA Mysov, EI Ikonnikov, NS Kuznetsov, NY Belokon, YN
Citation
Ab. Terent'Ev et al., Reformatsky-type addition of esters of alpha-halogeno carboxylic acids to aldehydes and ketones in the presence of Fe(CO)(5), RUSS CHEM B, 48(6), 1999, pp. 1121-1127
Citations number
22
Categorie Soggetti
Chemistry
Journal title
RUSSIAN CHEMICAL BULLETIN
ISSN journal
10665285 → ACNP
Volume
48
Issue
6
Year of publication
1999
Pages
1121 - 1127
Database
ISI
SICI code
1066-5285(199906)48:6<1121:RAOEOA>2.0.ZU;2-A
Abstract
Reformatsky-type addition of esters of a-halogeno carboxylic acids to aldeh ydes and ketones in the presence of Fe(CO)(5) and an activating agent (CBrC l3 or I-2) afforded the corresponding esters of beta-hydroxy acids in good yields. Possible reaction mechanisms are discussed.