Synthesis of cyclohexanone oxime from cyclohexanone and ammonia

Synthesis of cyclohexanone oxime was carried out by use only of cyclohexano ne and ammonia gas. Na-ZSM-5 catalyst showed remarkably high activity. It i s considered that the basic sites around the sodium cation inside Na-ZSM-5 were active sites for this reaction. Pyridine derivatives formed by aldol c ondensation were the main byproducts. Well-selected reaction conditions suc h as temperature, reaction time, and feed ratio can enhance the selectivity to cyclohexanone oxime.