Insoluble Polymer-Bound (IPB) approach to the catalytic asymmetric dihydroxylation of alkenes

Asymmetric dihydroxylation induced by Insoluble Polymer-Bound (IPB approach ) Cinchona alkaloid derivatives is re viewed. Reactivities and enantioselec tivities comparable to those achieved with the soluble counterparts are obt ained with polymers having structural properties compatible with the reacti on conditions. By using a highly efficient polymer, olefins with different structures can be dihydroxylated at a synthetically useful level of enantio selectivity. Handling and recovery of the catalyst is very easy; recycling is performed with a small amount of metal.