Triazenes: A useful protecting strategy for sensitive secondary amines

Authors
Lazny, R Poplawski, J Kobberling, J Enders, D Brase, S
Citation
R. Lazny et al., Triazenes: A useful protecting strategy for sensitive secondary amines, SYNLETT, (8), 1999, pp. 1304-1306
Citations number
14
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNLETT
ISSN journal
09365214 → ACNP
Issue
8
Year of publication
1999
Pages
1304 - 1306
Database
ISI
SICI code
0936-5214(199908):8<1304:TAUPSF>2.0.ZU;2-L
Abstract
The application of aryl triazene as a protecting group for sensitive second ary amines such as 4-piperidone (2) is described. The triazene,ene protecte d amine is compatible with oxidative and reductive conditions as well as wi th lithiating and alkylating reagents. The free amine is regenerated by tre atment with trifluoroacetic acid.