Asymmetric total synthesis of (-)-prosophylline

Authors
Koulocheri, SD Haroutounian, SA
Citation
Sd. Koulocheri et Sa. Haroutounian, Asymmetric total synthesis of (-)-prosophylline, TETRAHEDR L, 40(37), 1999, pp. 6869-6870
Citations number
11
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
00404039 → ACNP
Volume
40
Issue
37
Year of publication
1999
Pages
6869 - 6870
Database
ISI
SICI code
0040-4039(19990910)40:37<6869:ATSO(>2.0.ZU;2-6
Abstract
The asymmetric total synthesis of (-)-prosophylline from D-glucal via (2S)- hydroxymethyl-dihydropyridone 6 by a 17-step synthesis and 12% overall yiel d is presented. (C) 1999 Elsevier Science Ltd. All rights reserved.