Ya. Zhang et al., A toxic extract from sea urchin (T-pileolus) inhibits Ca-45(2+) uptake in P-2 fraction from chick brain under physiological ionic conditions, TOXICON, 37(11), 1999, pp. 1639-1643
An acidic toxic extract from the sea urchin T. pileolus inhibited time-depe
ndent Ca-45(2+) uptake in chick P-2 fraction (IC50 about 10 ng/ml). This to
xic extract is susceptible to trypsin. The inhibitory effect probably relat
e to Na+/Ca2+ exchanger. (C) 1999 Elsevier Science Ltd. All rights reserved
.