Treatment changes in prostatic hyperplasia and cancer, including androgen deprivation therapy and radiotherapy

Treatment changes in the benign and cancerous prostate present great diagno stic challenges in pathologic interpretation. The urologist must provide th e pertinent history of androgen deprivation or radiotherapy to assist the p athologist in understanding these changes to avoid misdiagnosis. This artic le describes the spectrum of treatment changes in the prostate resulting fr om hormonal therapy and radiotherapy, with an emphasis on the identificatio n of adenocarcinoma and its mimics.