R. Axer-siegel et al., Simultaneous indocyanine green and fluorescein angiography in retinal pigment epithelium tear using the confocal scanning laser ophthalmoscope, AM J OPHTH, 128(3), 1999, pp. 331-339
PURPOSE: To describe the indocyanine green angiographic pattern of retinal
pigment epithelium tears in the setting of age-related macular degeneration
compared with the fluorescein angiographic features.
METHODS: Twelve consecutive patients (12 eyes) with a retinal pigment epith
elium tear underwent simultaneous indocyanine green angiography and fluores
cein angiography with the confocal scanning laser ophthalmoscope. The findi
ngs for the two modes were compared,
RESULTS: Choroidal neovascular membrane was evident beneath the rolled reti
nal pigment epithelium on indocyanine green angiograms in 11 (92%) of 12 ey
es: a focal neovascular membrane was apparent in five (42%) of 12 eyes, whe
reas a plaque neovascular membrane was seen in six (50%) of 12 eyes. In com
parison, fluorescein angiography demonstrated late leakage as a result of o
ccult choroidal neovascular membrane in nine (82%) of 11 eyes but no well-d
efined choroidal neovascular membrane.
CONCLUSIONS: Indocyanine green angiography is superior to fluorescein angio
graphy for imaging choroidal neovascularization in cases of retinal pigment
epithelium tear and may serve as an important adjunct to indocyanine green
-guided laser treatment in selected cases. (Am J Ophthalmol 1999;128:331-33
9. (C) 1999 by Elsevier Science Inc. All rights reserved.)