ASYMMETRIC HYDROLYZES OF 1,2-DIACETOXYCYCLOHEXANES AND 1,3-DIACETOXYCYCLOHEXANES WITH THE CULTURED SUSPENSION CELLS OF MARCHANTIA-POLYMORPHA

Very high enantioselectivities were observed in the hydrolysis of race mic 1,2- and 1,3-diacetoxycyclohexanes and their derivatives by cultur ed cells of Marchantia polymorpha in suspension, Asymmetry was also in duced in the hydrolyses of meso-1,2 and 1,3-diacetates to the correspo nding monoacetates, These findings indicate that these cultured cells hydrolyze the acetoxyl groups enantioselectively at: the stereogenic c enter of R-configuration. Chirality 9:250-253, 1997. (C) 1997 Wiley-Li ss, Inc.