Factors affecting early postoperative feeding following elective open colon resection

Hypothesis: If factors accounting for the inability to tolerate early posto perative feeding after elective open colon resection can be identified, the n perhaps these factors can be modified to decrease future failures. Design: Consecutive case series. Setting: Tertiary referral center. Patients: From 1993 to 1998, 200 consecutive patients undergoing elective o pen colon resection. Intervention: Early postoperative feeding protocol consisting of clear liqu ids on the evening of postoperative dal: 2, regular diet on postoperative d ay 3, and discharged home as tolerated. A subgroup of patients was treated with metoclopramide. Main Outcome Measures: The ability to tolerate early feeding. Postoperative complications. Length of hospitalization. Results: Twenty-seven (13.5%) of the 200 patients failed to tolerate early feeding. 16 patients (8.0%) were immediately unable to tolerate oral intake , whereas 11 patients (5.5%) initially tolerated early postoperative feedin g but required hospital readmission due to emesis. There were no abdominal abscesses or anastomotic leaks. In patients who failed early feeding, no si gnificant differences were noted for age, comorbid medical illness, operati ve time, or additional surgical procedures, when compared with patients who tolerated early oral intake. However, 18 (20.9%) of the 86 men failed earl y feeding, compared with 5 (6.8%) of the 73 women (P = .01). Additionally, patients undergoing total abdominal colectomy or total proctocolectomy (n = II) failed 45.5% of the time, compared with 12.2% of the patients undergoi ng other types of colectomy (n = 189) (P = .01). The addition of metoclopra mide therapy did not significantly improve the ability to tolerate early fe eding. Conclusions: In patients undergoing elective open colon resection, early po stoperative feeding is safe and effective, and produces a brief hospital st ay compared with patients fed by traditional means. However, men and patien ts undergoing total abdominal colectomy are more likely to be intolerant of early postoperative feeding.