A new goat adenovirus isolate proposed as the prototype strain for goat adenovirus serotype 1

A virus isolated from the brain of a 3-year-old goat with encephalitis was identified as an adenovirus based on morphological and physicochemical char acteristics. Neutralization tests and restriction endonuclease analysis com paring the caprine adenovirus with the prototype ovine and bovine adenoviru s serotypes indicated that the caprine isolate was antigenically different and produced a unique restriction pattern and may represent a new adenoviru s species. A limited seroepidemiologic study using adult goat and sheep ser a collected from around the Unites States indicated that approximately 60 a nd 80 percent, respectively, had specific antibody for this isolate.