To develop an instrument to describe and quantify handicap caused by vision
impairment an item pool was derived from focus groups and from a review of
vision-related quality-of-life questionnaires. Only items related to handi
cap were included and grouped into five subscales. The 76-item 'Impact of V
ision Impairment' was administered to 95 people who were vision impaired. C
ontent validity was established by consultation with professionals and with
people with impaired vision. Forty-six items remained after the eliminatio
n of those found to be irrelevant and others with inter-item correlation co
efficients of greater than or equal to 0.7. Univariate and multivariate ana
lyses revealed an association between visual acuity and type and degree of
handicap on subscales, except emotional reaction to vision loss, which is r
elated to cause of vision impairment. The instrument is responsive to the l
evel of vision loss and discriminates the different performances of people
with different causes of vision loss.