A polymorphism in the CYP17 gene is associated with male breast cancer

Authors
Young, IE Kurian, KM Annink, C Kunkler, IH Anderson, VA Cohen, BB Hooper, ML Wyllie, AH Steel, CM
Citation
Ie. Young et al., A polymorphism in the CYP17 gene is associated with male breast cancer, BR J CANC, 81(1), 1999, pp. 141-143
Citations number
14
Categorie Soggetti
Oncology,"Onconogenesis & Cancer Research
Journal title
BRITISH JOURNAL OF CANCER
ISSN journal
00070920 → ACNP
Volume
81
Issue
1
Year of publication
1999
Pages
141 - 143
Database
ISI
SICI code
0007-0920(199909)81:1<141:APITCG>2.0.ZU;2-I
Abstract
The CYP17 gene codes for the cytochrome P450c17 alpha enzyme that is involv ed in the synthesis of oestrogens. This case-control study from the South E ast of Scotland shows that a polymorphism of the CYP17 gene is associated w ith an increased risk of male breast cancer.