Citation
F. Desangles et al., Translocation (X;1) associated with a nonpapillary carcinoma in a young woman: A new definition for an Xp11.2 RCC subtype, CANC GENET, 113(2), 1999, pp. 141-144
Citations number
25
Categorie Soggetti
Onconogenesis & Cancer Research
Journal title
CANCER GENETICS AND CYTOGENETICS
ISSN journal
01654608
→ ACNP
Volume
113
Issue
2
Year of publication
1999
Pages
141 - 144
Database
ISI
SICI code
0165-4608(199909)113:2<141:T(AWAN>2.0.ZU;2-2
Abstract
We report a transocation (X;1)(p11.2;q21) associated with a nontubulopapill
ary renal cell carcinoma in a 23-year-old woman. To our knowledge this the
first report of such an association. A review of the previously published c
ases of renal cell carcinoma with t(X;1) and its cytogenetic variants with
Xp11.2 anomalies is included. The role of this karyotype abnormality as a c
linical marker is discussed. The Xp11.2 abnormality could be a primary abno
rmality characterizing a particular type of RCC appearing in children and y
oung adults of both sexes and in which the histological aspect is not speci
fic. (C) Elsevier Science Inc., 1999. All rights reserved.