Nr. Welinder et al., PATHOGENESIS OF NONTRAUMATIC ATLANTOAXIAL SUBLUXATION (GRISELS-SYNDROME), European archives of oto-rhino-laryngology, 254(5), 1997, pp. 251-254
Non-traumatic atlanto-axial subluxation (AAS) is an uncommon complicat
ion of upper neck inflammatory processes and head and neck surgery. It
is also known under the eponym of Grisel's syndrome (GS). We present
a case report of a 6-year-old boy with GS that resulted from a retroph
aryngeal abscess. A diagnosis was not made until 2 months after the oc
currence of infection. Re-evaluation of repeated CT scans of the neck
showed the sequential development of AAS. These findings implied that
the pathogenesis of GS is a distention of the ligaments between the at
las and axis rather than loosening of the ligaments caused by the spre
ad of an inflammatory edema from the soft tissues of the neck as has b
een proposed by others.