Jp. Janssens et al., Effects of soft drink and table beer consumption on insulin response in normal teenagers and carbohydrate drink in youngsters, EUR J CAN P, 8(4), 1999, pp. 289-295
There is ample evidence that breast cancer susceptibility is induced during
the developmental stages of the human breast where, in a manner related to
sex-steroid hormones, insulin plays an important role. In turn, nutrition
might be implicated. Regular soft drinks and table beer, both carbohydrate-
containing drinks, are candidates affecting insulin concentrations. Eleven
teenagers, between the ages of 13 and 17 years, consumed a soft drink and a
table beer in a crossover study. The blood levels of insulin and glucose w
ere related to antropomorphometric and endocrine factors. In contrast to ta
ble beer, consumption of regular soft drinks induced a fast and dramatic in
crease in both glucose and insulin concentration within a maximum 1/2 hour
after consumption. The insulin response was linearly correlated to the body
mass index (BMI), Children with a small increase in BMI are highly sensiti
ve to regular soft drinks with regard to glucose and insulin response. The
finding suggests a vicious circle of high caloric drinks, increase in BMP a
nd insulin response. It is one of the nutritional pathways which might affe
ct susceptibility for breast cancer in youngsters. Table beer, a drink with
fermented sugars, does not share these effects on carbohydrate metabolism.
(C) 1999 Lippincott Williams & Wilkins.