Re-irradiation of head and neck tumors - Benefits and toxicities

Citation
A. Eisbruch et L. Dawson, Re-irradiation of head and neck tumors - Benefits and toxicities, HEMAT ONCOL, 13(4), 1999, pp. 825
Citations number
32
Categorie Soggetti
Hematology,"Cardiovascular & Hematology Research
Journal title
HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
ISSN journal
08898588 → ACNP
Volume
13
Issue
4
Year of publication
1999
Database
ISI
SICI code
0889-8588(199908)13:4<825:ROHANT>2.0.ZU;2-G
Abstract
Patients with recurrent or new primary head and neck tumors that have appea red in previously irradiated areas and that are nonresectable may be consid ered for a course of reirradiation. Selection of patients who are likely to benefit from reirradiation is important, taking into account the high risk of complications. Patients with a long time period since the first course of irradiation (preferably a minimum of one year), whose recurrent tumor is localized, and who do not manifest chronic tissue damage from the previous radiation course may benefit from reirradiation. Recurrent tumors arising in the larynx or nasopharynx may have better outcomes compared with other s ites. An aggressive therapeutic approach may cure some of these patients.