We study the left and right action of quaternionic numbers. The standard pr
oblems arising in the definitions of transpose, determinant, and trace for
quaternionic matrices are overcome. We investigate the possibility of formu
lating a new approach to quaternionic group theory. Our aim is to highlight
the possibility of looking at new quaternionic groups by the use of left a
nd right operators as fundamental step toward a clear and complete discussi
on of unification theories in physics.