Gm. Annunziata et al., CANDIDA (TORULOPSIS-GLABRATA) LIVER-ABSCESSES 8 YEARS AFTER ORTHOTOPIC LIVER-TRANSPLANTATION, Journal of clinical gastroenterology, 24(3), 1997, pp. 176-179
The authors report the case of a 48-year-old man in whom candida (Toru
lopsis glabrata) liver abscesses developed 8 years after liver transpl
antation. After a week of fever, computed tomography and Doppler ultra
sonography showed several fluid-filled loculations in the left lobe of
the liver and hepatic arterial stenosis. Aspirates from the abscesses
contained I glabrata organisms. This complication probably developed
because hepatic arterial stenosis resulted in bile infarcts (bilomas),
which were contaminated via the biliary tract with candida from the b
iliary-enteric anastomosis. Catheter drainage and administration of am
photericin B for 10 weeks permitted successful retransplantation. T. g
labrata liver abscesses, a life-threatening complication that can occu
r long after liver transplantation, can be successfully managed by agg
ressive medical treatment followed by retransplantation.