Efficacy of Shiunko for the treatment of atopic dermatitis

Shiunko is a typical Kampo drug made from herbal extracts and used to treat a range of conditions including atopic dermatitis. Shiunko, white petrolat um and 3.5% salt water were applied to the skin of atopic dermatitis patien ts, and their clinical effectiveness, and the changes in bacterial species and cell numbers on the skin were studied. Staphylococcus aureus was the ma in species seen but several other coagulase-negative staphylococci were als o identified on some patients. Shiunko was clinically effective in four of seven patients (57%) compared with no patients for petrolatum and one of se ven (14%) for salt water. Bacterial counts were reduced with Shiunko in fou r of seven patients compared with one of seven patients (14%) for both petr olatum and salt water. The results suggest that Shiunko may have antibacter ial effects on staphylococci, and may be an effective treatment for atopic dermatitis and other skin infections caused mainly by Staphylococcus specie s.