No biological advantage with a low temperature curing versus a conventional bone cement: an experimental, mechanical and histomorphometrical study inthe rabbit tibia

Both tibial marrow cavities of 12 rabbits were evacuated and filled with cu ring bone cement. In one of the tibias conventional curing bone cement (Sim plex P (R)) was injected, while the other tibia of the same animal was fill ed with a low temperature curing bone cement (Boneloc (R)). Three titanium implants were inserted along the proximal metaphysis of each tibia. Eight w eeks after insertion the most distal implant in each tibia was removed whil e recording the removal torque. The implant was then once again screwed hom e into its bone bed. The animals were sacrificed 16 weeks after implant ins ertion. The previously removed implant and another implant in each tibia we re then both removed while recording the removal torque. The third implant in each tibia was cut out en bloc with surrounding tissue and processed for ground section. We found no statistical differences in the mechanical or t he histomorphometric evaluation of implant integration between the two ceme nts, indicating that the low temperature curing bone cement does not result in a significantly different bone response from that of a conventional acr ylic cement. (C) 1999 Kluwer Academic Publishers.