H. Ben-ami et al., Reversible pancreatitis, hepatitis, and peripheral polyneuropathy associated with parenteral gold therapy, J RHEUMATOL, 26(9), 1999, pp. 2049-2050
A 63-year-old man with seronegative rheumatoid arthritis developed acute pa
ncreatitis, severe hepatitis, and sensorimotor polyneuropathy after receivi
ng 150 mg of intramuscular aurothioglucose (gold). Positive lymphocyte tran
sformation test to gold indicated a cell mediated hypersensitivity to the d
rug, while multiple investigations ruled out other underlying causes for hi
s illness. After cessation of gold therapy a complete recovery occurred.