M. Debboun et al., Laboratory evaluation of AI3-37220, AI3-35765, CIC-4, and deet repellents against three species of mosquitoes, J AM MOSQ C, 15(3), 1999, pp. 342-347
Citations number
41
Categorie Soggetti
Entomology/Pest Control
Journal title
JOURNAL OF THE AMERICAN MOSQUITO CONTROL ASSOCIATION
Four repellents, N,N-diethyl-3-methyl-benzamide (deet), 2-hydroxy-methyl-cy
clohexyl acetic acid lactone (CIC-4), and 2 piperidines (1-[3-cyclohexen-1-
ylcarbonyl] piperidine [AI3-35765] and 1-[3-cyclohexen-1-ylcarbonyl]-2-meth
ylpiperidine [AI3-37220]) were evaluated alone and in combination against A
edes aegypti, Anopheles stephensi, and Culex quinquefasciatus using a modif
ied in vitro test system. This method was a valuable tool for comparing eff
ective concentrations of the new compounds. Because of the controlled condi
tions of the test, it was possible to use the results of assays that had be
en conducted over a 5-year period and to perform the many replications nece
ssary to evaluate combinations of compounds. The new candidate repellents w
ere generally as effective as deet. Although speculative at this time, ther
e was some evidence of synergistic interaction. Repellent combinations of C
IC-4/AI3-37220/AI3-35767, deet/AI3-35765, and deet/AI3-37220/AI3-35765 agai
nst An. stephensi and CIC-4/AI3-35765, deet/AI3-37220/AI3-35765, AI3-37220/
AI3-35765, and CIC-4/AI3-37220 against Ae. aegypti were more effective than
the component compounds alone.