This paper examines the release of Tumour necrosis factor alpha, (TNFa
) interleukin 1, eicosanoids, and hydrogen peroxide from macrophages e
xposed to glove starch particles. Studies are described which show tha
t T-cell responses are potently activated by glove powder products lea
ding to the release and formation of high amounts of pro-inflammatory
mediators, ultimately resulting in adverse clinical consequences such
as starch peritonitis or adhesions.