J. Muller-berghaus et al., Artificial abdominal hernia for the treatment of hepatomegaly in a neonatewith stage 4S neuroblastoma, PED HEM ONC, 16(5), 1999, pp. 453-458
Surgical widening of the abdomen by a silastic pouch as been used very rare
ly in the management of critically ill infants with hepatomegaly due to neu
roblastoma stage 4S. A female newborn baby was referred on the second day o
f life because of local compressive effects of a massive hepatomegaly, whic
h lead to multiorgan failure. An artificial abdominal hernia was created on
the third day of life using a silastic pouch. During the operation oxygena
tion and ventilation improved and urinary output returned. After chemothera
peutic reduction of hepatic metastases and primary tumor the pouch was succ
essfully removed on day 57 without local complications. The child has survi
ved for more than 1 year and is in complete remission. An artificial abdomi
nal hernia should be considered more often in the critically ill neonate wi
th stage 4S neuroblastoma and massive hepatomegaly.