Kinetics of desolvation of related organic inclusion compounds

This study dealt mainly with the structure-reactivity relationship of selec ted organic inclusion compounds. The crystal structures of the inclusion co mpounds of three related hosts, 2,2'-bis(2,7-ditert-butyl-9-hydroxy-9-fluor enyl) biphenyl, 2,2/-bis (2,7-dichloro-9-hydroxy-9-fluorenyl)biphenyl and 2 , 2'-bis(2,7-dibromo-9-hydroxy-9-fluorenyl)biphenyl with 1,4-dioxane (Compo und 1), 1,3-dioxane (Compound 2) and 1,3-dioxolane (Compound 3) respectivel y were elucidated, using single crystal X-ray crystallography. It was found that the guests were either located in channels or constricted channels (c avities), formed by the host framework. The kinetics of desolvation of thes e compounds were studied and their activation energies were compared.