Structures of TMC-120A, B and C, novel isoquinoline alkaloids from Aspergillus ustus TC 1118

Authors
Kohno, J Hiramatsu, H Nishio, M Sakurai, M Okuda, T Komatsubara, S
Citation
J. Kohno et al., Structures of TMC-120A, B and C, novel isoquinoline alkaloids from Aspergillus ustus TC 1118, TETRAHEDRON, 55(37), 1999, pp. 11247-11252
Citations number
4
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
37
Year of publication
1999
Pages
11247 - 11252
Database
ISI
SICI code
0040-4020(19990910)55:37<11247:SOTBAC>2.0.ZU;2-E
Abstract
Three novel isoquinoline alkaloids, TMC-120A, B and C (1-3) have been isola ted from a fermentation broth of Aspergillus ustus (Bain.) Them & Church TC 1118, a fungus isolated from rhizosphere of grass. Their structures were d etermined through extensive spectroscopic analyses and chemical studies. TM C-120s (1-3) are found to be the first furo[3,2-h]isoquinoline-type alkaloi ds isolated from natural sources, (C) 1999 Elsevier Science Ltd. Ail rights reserved.