Studies on carbohydrates. Part 33: Synthesis of spacer-armed 2-acetamido-2-deoxy-4-O-beta-D-galactopyranosyl-alpha-D-mannosides and their dimers

Authors
Li, Q Li, H Cai, MS Li, ZJ Zhou, RL
Citation
Q. Li et al., Studies on carbohydrates. Part 33: Synthesis of spacer-armed 2-acetamido-2-deoxy-4-O-beta-D-galactopyranosyl-alpha-D-mannosides and their dimers, TETRAHEDR-A, 10(14), 1999, pp. 2675-2683
Citations number
15
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON-ASYMMETRY
ISSN journal
09574166 → ACNP
Volume
10
Issue
14
Year of publication
1999
Pages
2675 - 2683
Database
ISI
SICI code
0957-4166(19990716)10:14<2675:SOCP3S>2.0.ZU;2-M
Abstract
The mixture of 3,6-di-O-acetyl-4-0-(2,3,4,6-tetra-O-acetyl-beta-D-galactopy ranosyl)-2-azido-2-deoxy-Dpyranosyl 1-acetates or 1-trichloroacetates and t he corresponding mannose type glycosyl donors reacted with the spacer arms di- and triethylene glycol, in dichloromethane solution with BF3. OEt2 and TMSOTf as promoters at room temperature to give highly selective products. Only the mannose type products were obtained. (C) 1999 Elsevier Science Ltd . All rights reserved.