The objective of this prospective, cohort study was to compare the nut
ritional status of full-term infants who were fed human milk (BF, n =
29), formula (FF, n = 30) or evaporated milk formulae (EM, n = 30) for
at least 3 months. Infants were seen at enrollment, 3 and 6 months, a
t which times a blood sample, diet record and anthropometric data were
collected. Infants in the EM group received solids earlier (12 +/- 5
weeks) than did FF infants (15 +/- 4 weeks), and both were earlier tha
n BF infants (19 +/- 4 weeks). Only 26% of the EM fed group received i
ron supplements as ferrous sulphate drops. Seven BF, 12 FF and 20 EM h
ad abnormal ferritin values (<10 ng ml(-1)) at 6 months. Copper intake
was lower in the EM infants at 3 and 6 months. However, plasma copper
and erythrocyte copper zinc superoxide dismutase (ZnCuSOD) levels did
not differ between groups. Selenium intake was lower in the EM group
(5 +/- 1 and 10 +/- 5 mu g d(-1); 3 and 6 months) than in the FF infan
ts (13 +/- 4 and 19 +/- 7 mu g d(-1); 3 and 6 months). Erythrocyte SeG
HSPx levels in EM infants were lower at 6 months (EM, 33.2 +/- 3.4; FF
, 35.2 +/- 3.9; BF, 36.1 +/- 3.8 mU mg Hb(-1)). Thiamin intake (0.99 /- 0.08 and 1.24 +/- 0.32; 3 and 6 months, mg 1000 kcal(-1)) was highe
r in the FF group than in EM infants (0.38 +/- 0.39 and 0.66 +/- 0.38;
3 and 6 months). There were more (13%) abnormal thiamin assays in the
EM group at 6 months than in the BF and FF infants (0%). In conclusio
n, infants fed evaporated milk formula receive adequate copper but may
not receive enough thiamin or selenium. Unless supplemented from birt
h with medicinal iron, intakes of iron will be inadequate.