In the national Drug Abuse Treatment Outcome Studies (DATOS), many clients
in outpatient methadone treatment (OMT) and outpatient drug-free (ODF) moda
lities were admitted with multiple sex and needle-risk behaviors, but they
reduced these risks significantly during treatment. Using hierarchical line
ar model regression analysis, we examined client and treatment program char
acteristics as predictors of initial risk levels and of reductions over tim
e. Clients who used cocaine frequently before treatment or had antisocial p
ersonality disorder entered treatment with elevated risks. In both modaliti
es, cocaine users reduced risky behaviors significantly, but antisocial cli
ents did so only in OMT. Treatment programs located in cities with higher p
revalence rates of HIV/AIDS admitted clients with lower baseline levels of
risk behavior than found in other cities. OMT programs in lower prevalence
cities achieved higher rates of risk reduction than programs in higher prev
alence cities. Reduction of sex and needle risks in both the Oh rr and ODF
modalities indicates the importance of outpatient drug abuse treatment to n
ational HIV prevention policy.