Hip fracture incidence rates are predicted to increase dramatically in the
first half of the 21st century, especially in Asia, Latin America, Africa,
and the Middle East. These increased rates will result primarily from the e
ffects of public health efforts to improve nutrition and infectious-disease
control, both of which contribute to improved longevity of populations. An
example of a rapid increase in hip fracture incidence rates has been repor
ted in Hong Kong. Findings of studies there suggest that environmental chan
ges, ie, westernization, urbanization, or both, are strongly related with d
eclines in bone mineral density and increases in fractures. Hip fracture in
cidence rates in Western nations are typically increasing at much more mode
st rates than those in Hong Kong and other Asian nations. Epidemiologic inv
estigations have identified multiple risk factors, including exposures earl
ier in life to adverse factors that are considered to contribute to the dev
elopment of osteoporosis in both Western and Asian nations. The major risk
factors are inadequate nutrition, limited physical activity, and low lifeti
me estrogen exposure. A dietary shift toward a more plant-based diet in Wes
tern nations may be beneficial to bone health, but is not likely to counter
the adverse effects of limited physical activity and low estrogen exposure
.