In vitro activities of fluoroquinolones against antibiotic-resistant bloodculture isolates of viridans group streptococci from across Canada

Authors
de Azavedo, JCS Trpeski, L Pong-Porter, S Matsumura, S Low, DE
Citation
Jcs. De Azavedo et al., In vitro activities of fluoroquinolones against antibiotic-resistant bloodculture isolates of viridans group streptococci from across Canada, ANTIM AG CH, 43(9), 1999, pp. 2299-2301
Citations number
22
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
00664804 → ACNP
Volume
43
Issue
9
Year of publication
1999
Pages
2299 - 2301
Database
ISI
SICI code
0066-4804(199909)43:9<2299:IVAOFA>2.0.ZU;2-R
Abstract
Among 418 blood culture isolates of viridans group streptococci obtained be tween 1995 and 1997, the in vitro rates of nonsusceptibility to penicillin, erythromycin, tetracycline, and trimethoprim-sulfamethoxazole were 28, 29, 24, and 14%, respectively. The most prevalent group (125 strains) was Stre ptococcus mitis, followed by Streptococcus sanguis (56 strains). For 236 (5 6%) strains resistant to one or more antibiotics, the ciprofloxacin MIC at which 90% of the isolates were inhibited (MIC90) was 4 mu g/ml, whereas the MIC(90)s of trovafloxacin, grepafloxacin, and gatifloxacin were 0.25 mu g/ ml.