Clostridium difficile cell attachment is modified by environmental factors

Authors
Waligora, AJ Barc, MC Bourlioux, P Collignon, A Karjalainen, T
Citation
Aj. Waligora et al., Clostridium difficile cell attachment is modified by environmental factors, APPL ENVIR, 65(9), 1999, pp. 4234-4238
Citations number
34
Categorie Soggetti
Biology,Microbiology
Journal title
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
ISSN journal
00992240 → ACNP
Volume
65
Issue
9
Year of publication
1999
Pages
4234 - 4238
Database
ISI
SICI code
0099-2240(199909)65:9<4234:CDCAIM>2.0.ZU;2-2
Abstract
Adherence of Clostridium difficile to Vero cells under anaerobic conditions was increased by a high sodium concentration, calcium-rich medium, an acid ic pH, and iron starvation. The level of adhesion of nontoxigenic strains w as comparable to that of toxigenic strains. Depending on the bacterial cult ure conditions, Vero cells could bind to one, two, or three bacterial surfa ce proteins with molecular masses of 70, 50, and 40 kDa.