H. Nishijo et al., SINGLE NEURON RESPONSES IN THE MONKEY ANTERIOR CINGULATE CORTEX DURING VISUAL-DISCRIMINATION, Neuroscience letters, 227(2), 1997, pp. 79-82
Single neuron activity was recorded from the monkey anterior cingulate
cortex during operant behavior based on discrimination of rewarding,
aversive, and neutral objects. Of 550 neurons recorded, 116 responded
during the task; 36, during visual discrimination; 40, during bar pres
sing for operant responding. Of these, 26 vision-related neurons respo
nded differentially to rewarding, aversive and neutral objects, and 11
bar press-related neurons differentiated bar pressing to avoid shock
from bar pressing to obtain reward. Responses of these neurons depende
d on associative meaning (aversive or rewarding) of the objects since
these neuronal responses were modulated by the reversal learning. The
results provide neuronal bases for involvement of the anterior cingula
te cortex in emotional and motivational processes. (C) 1997 Elsevier S
cience Ireland Ltd.