Molecular cloning and expression of human neurochondrin-1 and-2

Authors
Mochizuki, R Ishizuka, Y Yanai, K Koga, Y Fukamizu, A
Citation
R. Mochizuki et al., Molecular cloning and expression of human neurochondrin-1 and-2, BBA-GENE ST, 1446(3), 1999, pp. 397-402
Citations number
13
Categorie Soggetti
Molecular Biology & Genetics
Journal title
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION
ISSN journal
01674781 → ACNP
Volume
1446
Issue
3
Year of publication
1999
Pages
397 - 402
Database
ISI
SICI code
0167-4781(19990903)1446:3<397:MCAEOH>2.0.ZU;2-B
Abstract
Human neurochondrins have been cloned from a brain cDNA library. The human neurochondrin-1 and -2 predict leucine-rich (15.8 and 15.9%) proteins of 72 9 and 712 amino acid residues, with molecular weights of 78.9 and 77.2 kDa, respectively. The deduced amino acid sequence indicates 98% identity among human, mouse and rat species. Northern analysis indicates that about 4 kb human neurochondrin mRNAs are abundant in the fetal and the adult brain. (C ) 1999 Elsevier Science B.V. All rights reserved.