Jh. Kim et al., H2O2 resistance is linked to the degree of fatty acid unsaturation in Streptomyces coelicolor A3(2), BIOTECH LET, 21(9), 1999, pp. 759-762
In Streptomyces coelicolor A3(2), as the content of palmitoleic acid increa
sed with decreasing growth temperature, H2O2 resistance decreased. Producti
on of thiobarbituric acid-reactive substances upon H2O2 treatment was incre
ased by supplementing unsaturated fatty acids. Therefore, the content of pa
lmitoleic acid is a determining factor for the survival of Streptomyces coe
licolor A3(2) subjected to H2O2 stress.