Inappropriate antidiuretic hormone secretion after high-dose thiotepa

Authors
Sica, S Cicconi, S Sora, F Chiusolo, P Piccirillo, N Laurenti, L La Barbera, EO Giordano, G Leone, G
Citation
S. Sica et al., Inappropriate antidiuretic hormone secretion after high-dose thiotepa, BONE MAR TR, 24(5), 1999, pp. 571-572
Citations number
3
Categorie Soggetti
Hematology,"Medical Research Diagnosis & Treatment
Journal title
BONE MARROW TRANSPLANTATION
ISSN journal
02683369 → ACNP
Volume
24
Issue
5
Year of publication
1999
Pages
571 - 572
Database
ISI
SICI code
0268-3369(199909)24:5<571:IAHSAH>2.0.ZU;2-H
Abstract
High-dose thiotepa has been successfully included in a variety of condition ing regimens for stem cell transplantation in hematological and solid neopl asms. Toxicity of high-dose thiotepa mainly manifests as profound myeloabla tion and some degree of liver damage. We report a case of inappropriate sec retion of antidiuretic hormone (SIADH) in a patient with primary CNS lympho ma who underwent therapy with high-dose thiotepa.