Mj. Wearne et al., Comparison of dacryocystography and lacrimal scintigraphy in the diagnosisof functional nasolacrimal duct obstruction, BR J OPHTH, 83(9), 1999, pp. 1032-1035
Aim-It appears from the literature that no standardised examination exists
for patients with functional nasolacrimal duct obstruction. The role of dac
ryocystography and lacrimal scintigraphy was compared in the diagnosis and
management of these patients.
Method-Patients who were clinically diagnosed as having unilateral or bilat
eral functional nasolacrimal duct obstruction were prospectively entered in
to the study and data collected over 12 months in Moorfields Eye Hospital a
nd Whipps Cross Hospital, London. All cases had, on separate occasions, a s
tandardised dacryocystogram with delayed erect films and a lacrimal drainag
e scintigram.
Results-45 lacrimal systems of 32 patients (mean age 62 years; 59% male) fu
lfilled the inclusion criteria. Abnormalities were detected with dacryocyst
ography in 93% of systems and with lacrimal drainage scintigraphy in. 95% o
f systems, Based on the results of previous quantitative studies, the posit
ive scintigrams were subdivided into those demonstrating prelacrimal sac de
lay (13%), delay at the lacrimal sac/duct junction (35%), or delay within t
he duct (47%). Combining the two imaging techniques increased the sensitivi
ty to 98%.
Conclusions-Bath investigations are very sensitive at detecting abnormaliti
es in patients with a clinical diagnosis of functional nasolacrimal duct ob
struction. Lacrimal drainage scintigraphy is a slightly more sensitive test
, but missed an abnormality detected by dacryocystography in two (4%) syste
ms. A combination of the two techniques gives the highest sensitivity with
maximum anatomical and physiological information but, in clinical practice,
his reasonable to perform a dacryocystogram initially and proceed to scint
igraphy only if contrast radiography is normal.