Comparison of MR spectroscopy and MR imaging with contrast agent in children with cerebral astrocytomas

Authors
Dezortova, M Hajek, M Cap, F Babis, M Tichy, M Vymazal, J
Citation
M. Dezortova et al., Comparison of MR spectroscopy and MR imaging with contrast agent in children with cerebral astrocytomas, CHILD NERV, 15(8), 1999, pp. 408-412
Citations number
16
Categorie Soggetti
Pediatrics
Journal title
CHILDS NERVOUS SYSTEM
ISSN journal
02567040 → ACNP
Volume
15
Issue
8
Year of publication
1999
Pages
408 - 412
Database
ISI
SICI code
0256-7040(199908)15:8<408:COMSAM>2.0.ZU;2-S
Abstract
We studied 33 patients with astrocytomas of different grades (68 examinatio ns) by magnetic resonance imaging (MRI) and proton MR spectroscopy (H-1-MRS ). We found that in 80% of the spectra, the presence of signals in the area of 0.8-1.5 ppm, assigned to lipids/lactate in H-1-MR spectra, correlated w ith signal enhancement after Cd-DTPA administration. Mie suggest that visib ility of lipid/lactate signals could be due to blood-brain barrier damage, which is characterized by contrast agent enhancement.