In this paper it is proved that the index of a Fredholm operator between p-
adic Banach spaces is preserved under compact perturbations. A case of spec
ial interest is provided when the ground field is nonspherically complete.
In this case the classical techniques are no longer valid and the relation
between the kernels of a Fredholm operator and that of a small compact pert
urbation turn out to be in general much richer than in the complex context.