Will the genetic individualization of disease force a new paradigm?

Authors
Citation
Rl. Nagel, Will the genetic individualization of disease force a new paradigm?, CR AC S III, 322(1), 1999, pp. 1-4
Citations number
9
Categorie Soggetti
Multidisciplinary,"Experimental Biology
Journal title
COMPTES RENDUS DE L ACADEMIE DES SCIENCES SERIE III-SCIENCES DE LA VIE-LIFE SCIENCES
ISSN journal
07644469 → ACNP
Volume
322
Issue
1
Year of publication
1999
Pages
1 - 4
Database
ISI
SICI code
0764-4469(199901)322:1<1:WTGIOD>2.0.ZU;2-8
Abstract
Disease, through the ages, has been considered as a 'visitation' from afar to the body or as 'disequilibrium' of an internal order. In practical terms , these two concepts of disease have generated a nosology, that is a classi fication of disease states. Genetics, in its dazzling recent advances, has opened another conceptual framework: disease is an individual event, inasmu ch as our growing understanding of the genetic 'terrain' makes all subjects true individuals. Hence, it is time to abandon the old conceptual dichotom y for a Hegelian synthesis: there are no diseases (either as visitation or disequilibrium) only diseased individuals. ((C) Academie des sciences / Els evier, Paris.).