CALCIUM INFLUX DURING HYPOXIA REOXYGENATION IN PRIMARY CULTURED RAT HEPATOCYTES - PROTECTIVE EFFECT OF UNIVERSITY-OF-WISCONSIN SOLUTION/

Authors
CRENESSE D HUGUES M FERRE C POIREE JC DOLISI C GUGENHEIM J
Citation
D. Crenesse et al., CALCIUM INFLUX DURING HYPOXIA REOXYGENATION IN PRIMARY CULTURED RAT HEPATOCYTES - PROTECTIVE EFFECT OF UNIVERSITY-OF-WISCONSIN SOLUTION/, Cryo-letters, 18(3), 1997, pp. 143-152
Citations number
32
Categorie Soggetti
Biology Miscellaneous",Physiology
Journal title
Cryo-letters → ACNP
ISSN journal
01432044
Volume
18
Issue
3
Year of publication
1997
Pages
143 - 152
Database
ISI
SICI code
0143-2044(1997)18:3<143:CIDHRI>2.0.ZU;2-O
Abstract
Primary cultures of rat hepatocytes were used to simulate successions of warm (as in liver surgery) or cold (as in liver transplantation) hy poxia and reoxygenation phases (in culture medium or in University of Wisconsin solution). During warm hypoxia/reoxygenation, calcium influx es were higher than during cold hypoxia/reoxygenation and UW protected hepatocytes from calcium invasion which was deleterious for these cel ls.