Cerebral metastases in malignant mesothelioma: a case report

A case of a 61-year-old man with metastatic malignant mesothelioma is descr ibed. Four months after diagnosis the patient commenced chemotherapy with l iposomal doxorubicin as part of an EORTC phase II trial. He developed signs of intracerebral metastases after his fourth cycle of chemotherapy and die d shortly after. Malignant mesothelioma is traditionally viewed as a diseas e that spreads locally but metastasizes rarely. We describe in detail this case and suggest that metastases in this disease are not as common as origi nally proposed.