RADIOIODINATED ABSCISIC-ACID PHOTOAFFINITY PROBE

Citation
Ad. Kohler et al., RADIOIODINATED ABSCISIC-ACID PHOTOAFFINITY PROBE, Journal of the Chemical Society. Perkin transactions. I, (10), 1997, pp. 1543-1547
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
ISSN journal
0300922X
Issue
10
Year of publication
1997
Pages
1543 - 1547
Database
ISI
SICI code
0300-922X(1997):10<1543:RAPP>2.0.ZU;2-6
Abstract
The construction of a photoaffinity probe based on abscisic acid is de scribed. A strategy based on C-4'-tethering of aromatic hydrazides led to abscisic acid 4'-(3 ''-azido-4 ''-hydroxybenzoylhydrazide). This c ompound is of moderate biological activity in cereal aleurone assays a nd was readily iodinated with chloramine T and sodium iodide, conditio ns that were used for the preparation of the [I-125]-labelled compound in high radiochemical yield.