V. Violi et al., Total anorectal reconstruction by double graciloplasty: experience with delayed, selective use of implantable pulse generators, INT J COL R, 14(3), 1999, pp. 164-171
This study reports our experience with total anorectal reconstruction (TAR)
, supported at a later phase, whenever necessary, by an implantable pulse g
enerator. Thirteen patients underwent total anorectal reconstruction by dou
ble graciloplasty, diverting loop colostomy, and implantation of temporary
electrodes. External-source, short-term, intermittent electrostimulation an
d biofeedback were used for neosphincter voluntary control training. After
abdominal stoma closure, 6 months after initial surgery in disease-free pat
ients, functional results were evaluated by a scoring system and anomanomet
ry A pulse generator was implanted whenever continence was judged unsatisfa
ctory. After continuous electrostimulation training, neosphincter function
was reassessed. Major graciloplasty complications (partial muscle necrosis
and perineal colostomy necrosis) were treated successfully by surgery. One
death of myocardial infarction occurred after discharge. Three patients ref
used further surgery. One patient did not undergo abdominal stoma closure b
ecause of early hepatic metastases. Functional evaluation after closure (ei
ght patients) showed the following results: two "excellent" (no pulse gener
ator implanted), three "good" (two stimulator implantations, with an "excel
lent" result), two "fair", and one "poor" (3 implantations, with a "good" r
esult). In addition to improving clinical results (P=0.042), resting anal p
ressures were also increased significantly by active an implantable pulse g
enerator (P=0.043). Although stimulators, whenever implanted, improved the
neosphincter function, delayed, selective use of these in some cases render
ed an implantable pulse generator either unnecessary from a functional view
point or redundant because of cancer recurrence or infectious complications
. Drawbacks to the procedure were poor patient complicance to neosphincter
training and to multiple surgical procedures, and excessive wasting of huma
n resources during training for intermittent electrostimulation and biofeed
back.