Template synthesis of rotaxanes with carbamate-linked axles

Proceeding from diisocyanates 4 and 10-13, (4-hydroxyphenyl )triphenylmetha ne 14 and tetralactame macrocycles 1, 2 and 9 the threading synthesis of ro taxanes 16-21 containing carbamate units in the axle is described. In addit ion to aromatic diisocyanates aliphatic ones are firstly introduced as buil ding blocks in rotaxane chemistry. The template synthesis of the new tetral actame macrocycle 9 with a pyridine unit is presented. It is used as wheel in a rotaxane synthesis towards the carbamate-linked rotaxane 21.