H. Imaizumi et al., T-for-H exchange reaction between HTO vapor and two functional groups in an aromatic compound in a gas-solid system, J RAD NUCL, 241(3), 1999, pp. 451-455
The hydrogen-isotope exchange reaction (T-for-H exchange reaction) between
HTO vapor and an aromatic compound having two different kinds of functional
groups has been observed at several temperatures. The rate constant (k) fo
r each functional group in the T-for-H exchange reaction was obtained by us
ing both the A "-MCKAY plot method and the data observed. Comparing these k
with each other has led to the following four conclusions in the T-for-H e
xchange reaction. (1) The reactivity of both the COOH and OH groups increas
es with a rise in temperature. (2) As to the degree of the effect of the CO
OH group on the reactivity of monosubstituted phenols, the degree in p-hydr
oxybenzoic acid is greater than that in m-hydroxybenzoic acid. (3) The HAMM
FIT rule is useful for estimating the reactivity of a certain aromatic comp
ound. (4) The A "-MCKAY plot method is also useful not only investigating t
he reactivity of the compounds having one kind of functional group, but als
o doing the reactivity of the compounds having two different kinds of funct
ional groups.