Breed, sex, and body weight as risk factors for rupture of the cranial cruciate ligament in young dogs

Objective-To describe clinical features of dogs < 2 years old with rupture of the cranial cruciate ligament (CCL) and to evaluate breed, sex, and body weight as risk factors. Design-Case-control study. Animals-201 dogs < 2 years old with rupture of the CCL and 804 age-matched control dogs. Procedure-Medical records were reviewed for breed, sex, and body weight, an d results were compared with results of age-matched control dogs. Results-Breed predisposition was detected for Neapolitan Mastiff. Akita, Sa int Bernard, Rottweiler, Mastiff. Newfoundland, Chesapeake Bay Retriever, L abrador Retriever, and American Staffordshire Terrier. Increased risk was d etected for neutered males and neutered females, compared with sexually int act males and sexually intact females, respectively. Differences in prevale nce of rupture of the CCL were not detected between all males and females, sexually intact males and sexually intact females, or neutered males and ne utered females. Body weights of dogs with ruptured CCL were significantly g reater than those of control dogs. Conclusions and Clinical Relevance-Several large breeds of dogs are predisp osed to rupture of the CCL at a young age.