Purpose: This study was undertaken to determine the appropriate timing and
frequency of duplex ultrasound scanning after carotid endarterectomy (CEA)
for the detection of high-grade stenosis caused by recurrent carotid stenos
is or contralateral atherosclerotic disease progression.
Methods: In 221 patients who underwent 242 CEAs, duplex scanning was perfor
med before, during, and after operation (in 3-month to 6-month intervals).
High-grade internal carotid artery (ICA) stenosis (peak systolic velocity,
>300 cm/s; diastolic velocity, >125 cm/s; ICA/common carotid artery ratio,
>4) prompted the recommendation for repair. An average of four postoperativ
e scanning procedures was performed during a mean follow-up period of 27.4
months.
Results: Intraoperative duplex scan results prompted the immediate revision
of 12 repairs (4.9%), and one perioperative stroke (<1%) occurred. Six CEA
s (2.7%) had asymptomatic recurrent stenosis (>50% diameter-reduction [DR];
systolic velocity, >125 cm/s) develop. Only one of six patients had >75% D
R stenosis develop and underwent reoperation (<1% yield for CEA surveillanc
e). The yield of surveillance of the unoperated ICA was higher (P =.003), a
nd 12% of unoperated sides had progressive stenosis (n = 21) or occlusion (
n = 3) develop, which led to seven CEAs for high-grade stenosis. Disease pr
ogression to >75% DR stenosis was five times as frequent (P =.002) in patie
nts with >50% DR stenosis initially. All patients but one who required cont
ralateral endarterectomy for disease progression had >50% ICA stenosis when
first seen. During the follow-up period, no disabling strokes ipsilateral
to an operated carotid artery occurred, but three strokes occurred in the h
emisphere of the contralateral unoperated ICA.
Conclusion: The yield of duplex scan surveillance after CEA was low. Only 1
3 patients (5.9%) had severe disease develop to warrant additional interven
tion. Progression of contralateral disease rather than restenosis was the m
ost common abnormality that was identified. Duplex scanning at 1-year to 2-
year intervals after CEA is adequate when a technically precise repair is a
chieved and minimal contralateral disease (<50% DR) is present. A policy of
duplex scan surveillance and reoperation for high-grade stenosis was assoc
iated with a 1.6% incidence rate of disabling stroke during the follow-up p
eriod.